导师简介
姓名 | 赵群 |
|
出生年月 | 1991年8月 | |
单位 | 湖北医药学院基础医学院 | |
所属学科 | 基础医学-药理学与毒理学 | |
职称、职务 | 副教授，硕士研究生导师， | |
zhaoqun@hbmu.edu.cn | ||
研究方向 | 1.细胞死亡死与炎癌发生机制 2. 抗炎药理学 | |
个人简介 | 赵群，女，1991年8月生，博士（后），副教授，硕士研究生导师，楚天学者（子）。从事细胞死亡死与炎癌发生机制以及抗炎、抗癌药理研究。 主持完成科研项目6项，其中国家自然科学基金项目1项。发表论文21篇，其中SCI收录论文22篇。 | |
代表作 | 1. Qun Zhao, Xianjun Yu, Haiwei Zhang, Yongbo Liu, Xixi Zhang, Xiaoxia Wu, Qun Xie, Ming Li, Hao Ying, Haibing Zhang *. RIPK3 mediates necroptosis during embryonic development and postnatal inflammation in fadd-deficient mice. Cell Reports. 2017;19(4):798-808（第一作者；影响因子9.423，生物1区，Top期刊） 2. Zhao Q, Guo J, Wang G, Bi Y, Cheng X, Liao Y, Jin S, Li L, Guo Y, Pan L, Zhang X, Tan Y, Zhou G *, Yu X *. CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signaling. Cancer Letters. 2021 Apr 21; 511:1-14. （第一作者；影响因子8.679，医学1区，Top期刊） 3. Qun Zhao #, Xianjun Yu #, Ming Li, Yongbo Liu, Yamei Han, Xixi Zhang, Xiaoming Li, Xiaoxia Wu, Jun Qin, Jing Fang, Haibing Zhang *. MLKL attenuates colon inflammation and colitis-tumorigenesis via suppression of inflammatory responses.Cancer Letters. 2019;459:100-111.（第一作者；影响因子8.679，医学1区，Top期刊） 4. Qun Zhao #, Yun Bi #, Jing Zhong, Xiang Li, Jian Guo, Ying-xiang Liu, Long-rui Pan, Yan Tan, Zhang-shuang Deng *, Xian-jun Yu *. 10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation. Acta Pharmacologica Sinica. 2021, 42(5), 791–800.（第一作者，影响因子6.1，医学1区，Top期刊，中国科技期刊卓越行动计划重点期刊）。 5. Qun Zhao , Yun Bi, Jian Guo, Yingxiang Liu, Jing Zhong, Longrui Pan, Yan Tan, Xianjun Yu *. Pristimerin protects against inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Acta Pharmacologica Sinica. 2021, 42(6), 975–986.（第一作者，影响因子6.1，医学1区，Top期刊，中国科技期刊卓越行动计划重点期刊） 6. Qun Zhao#, *, Jian Guo #, Xinran Cheng, Yingying Liao, Yun Bi, Yingxia Gong, Xudong Zhang, Yang Guo, Xianhui Wang, Wei Yu, Shu Jin, Yan Tan and Xianjun Yu*. RIPK3 suppresses the progression of spontaneous intestinal tumorigenesis. 2021, Frontiers in oncology, 11, 664927.（第一／通讯作者，影响因子6.244，医学2区） 7. Qun Zhao#, Xinran Cheng#, Wei Yu#, Yun Bi, Jian Guo, Qingzhao Ma, Yingxia Gong, Li He*, Xianjun Yu*. Pristimerin induces apoptosis and tumor inhibition of oral squamous cell carcinoma through activating ROS-dependent ER stress/Noxa pathway. Phytomedicine; 2021 Nov;92:153723 (第一作者；影响因子5.34；医学1区，TOP 期刊) 8. Qun Zhao # , Jing Zhong #, Yun Bi, Yongqiang Liu, Yingxiang Liu, Jian Guo, Longrui Pan, Yan Tan, Xianjun Yu *. Gambogenic acid induces Noxa-mediated apoptosis in colorectal cancer through ROS-dependent activation of IRE1α/JNK. Phytomedicine. 2020;78:153306.（第一作者，影响因子5.34，医学1区，Top期刊） 9. Qun Zhao #, Yun Bi #, Jian Guo, Yingxiang Liu, Jing Zhong, Yongqiang Liu, Longrui Pan, Yang Guo, Yan Tan, Xianjun Yu *. Effect of pristimerin on apoptosis through activation of ROS/endoplasmic reticulum (ER) stress-mediated Noxa in colorectal cancer. Phytomedicine. 2021;80:153399.（第一作者，影响因子5.34，医学1区，Top期刊） 10. Qun Zhao *, Xinran Cheng, Jian Guo, Yun Bi, Li Kuang, Jianhua Ren, Jing Zhong, Longrui Pan, Xudong Zhang, Yang Guo, Yongqiang Liu, Shu Jin, Yan Tan, Xianjun Yu *. MLKL inhibits intestinal tumorigenesis by suppressing STAT3 signaling pathway. International Journal of Biological Sciences. 2021; 17(3): 869-881.（第一／通讯作者，影响因子6.58，生物科学2区） 11. Qun Zhao #, Yingxiang Liu #, Jing Zhong, Yun Bi, Yongqiang Liu, Ziting Ren, Xiang Li, Junjun Jia, Mengting Yu, Xianjun Yu *. Pristimerin induces apoptosis and autophagy via activation of ROS/ASK1/JNK pathway in human breast cancer in vitro and in vivo. Cell Death Discovery. 2019; 5: 125.（第一作者，影响因子5.241，医学2区） 12. Qun Zhao, Yun Bi, Jing Zhong, Ziting Ren, Yingxiang Liu, Junjun Jia, Mengting Yu, Yan Tan, Qiufang Zhang, Xianjun Yu *. Pristimerin suppresses colorectal cancer through inhibiting inflammatory responses and Wnt/β-catenin signaling. Toxicology and applied pharmacology. 2020;386:114813.（第一作者，影响因子4.219，医学2区 | |
