导师简介
姓名 | 李丹丹 |
|
出生年月 | 1987年8月 | |
单位 | 湖北医药学院基础医学院 | |
所属学科 | 基础医学-实验肿瘤学 | |
职称、职务 | 副教授，硕士研究生导师 | |
E-mail | lidandan_cup@163.com | |
研究方向 | 胃癌的发生及转移分子机制 | |
个人简介 | 李丹丹，女，博士，副教授，硕士研究生导师。主持国家自然科学基金1项（在研），湖北省自然科学基金1项。近五年以第一作者或通讯作者发表高质量SCI论文9篇，包括Cell Death Disease（2022）、Oncogene（2021）、JECCR（2022）、Cell Proliferation（2023）、Cell Bioscience（2023）等知名期刊，累计影响因子>80。 | |
代表作 | 1. Li, Dandan, Shen Li, Zhang Xudong. et al. LncRNA ELF3-AS1 inhibits gastric cancer by forming a negative feedback loop with SNAI2 and regulates ELF3 mRNA stability via interacting with ILF2/ILF3 complex. J Exp Clin Cancer Res 41, 332 (2022). （中科院1区） 2. Li Dandan, Xia Lingyun, Huang Pan, Wang Zidi, Guo Qiwei, Huang Congcong, Leng Weidong, Qin Shanshan; Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms, Cell Prolif. 2023; e13423. （中科院1区） 3. Li, Dandan; Xu, Mengjie; Wang, Zidi; Huang, Pan; Huang, Congcong; Chen, Zhen; Tang, Gaijuan; Zhu, Xingji; Cai, Mengyu; Qin, Shanshan; The EMT-induced lncRNA NR2F1-AS1 positively modulates NR2F1 expression and drives gastric cancer via miR-29a-3p/VAMP7 axis., Cell Death & Disease, 2022, 13(1): 0-84. （中科院1区） 4.Li Dandan, She Jiajun, Hu Xinhui, Zhang Meixin, Sun Ruonan and Qin Shanshan*. ELF3-regulated lncRNA UBE2CP3 is over-stabilized by RNA-RNA interactions and drives gastric cancer metastasis via miR-138-5p/ITGA2 axis. Oncogene2021, 40(35): 5403-5415. （中科院1区） 5.Li, Dandan; Wang, Jingjie; Zhang, Meixin; Hu, Xinhui; She, Jiajun; Qiu, Xuemei; Zhang, Xudong; Xu, Li; Liu, Ying; Qin, Shanshan*; LncRNA MAGI2-AS3 Is Regulated by BRD4 and Promotes Gastric Cancer Progression via Maintaining ZEB1 Overexpression by Sponging miR-141/200a, Molecular Therapy-Nucleic Acids, 2020, 19: 109-123. （中科院1区） 6.Qin Shanshan*, Wang Zidi, Huang Pan, Huang Congcong, Li Dandan*: Serine protease PRSS23 drives gastric cancer by enhancing tumor associated macrophage infiltration via FGF2. Frontiers in immunology, 2022, 13: 955841. （中科院2区） 7.Li Dandan, Xia Lingyun, Huang Pan et al. Serine protease PRSS56, a novel cancer-testis antigen activated by DNA hypomethylation, promotes colorectal and gastric cancer progression via PI3K/AKT axis, Cell Biosci. 2023. （中科院2区） 8.Li Dandan, Xia Lingyun, Huang Pan, Wang Zidi, Guo Qiwei, Huang Congcong, Leng Weidong & Qin Shanshan. Cancer-associated fibroblast-secreted IGFBP7 promotes gastric cancer by enhancing tumor associated macrophage infiltration via FGF2/FGFR1/PI3K/AKT axis.Cell Death Discov.9, 17 (2023). （中科院2区） | |
