陈淼

单位

湖北医药学院基础医学院

所属学科

基础医学-生物化学与分子生物学

职称、职务

副教授-硕士研究生导师

E-mail

chenmiao@hbmu.edu.cn

研究方向

生物传感器的制备与应用；疾病致病机制与诊疗

个人简介

陈淼，男，1992年7月出生，博士，副教授，硕士研究生导师，湖北医药学院生化教研室。从事生物传感器的制备与应用；肿瘤、神经退行性疾病的诊断与治疗。主持省自然、教育厅、省级重点实验室、校级项目共计7项，以第一作者或第一通讯作者发表SCI论文共14篇。

代表作

（罗列近5年5篇代表作）

1.Li A.R, Yang Q, Zhu R.J, Zhang H, Qu Y, Li Y, Duan J, Luan J,  Peng K, Luo L, Li H, Sun X*, ChenC*,Chen M*, A high-sensitivity ESIPT-based fluorescent probe with a large stokes shift for H₂S detection and imaging in U251 cells and glioma mouse models. Bioorganic Chemistry,2026, 168, 109368.

2.Liu G, Zhang H, Tang B, Wang K, Qu Y, Luan J, Luo C, Dong X, Li J*, Shen L*,Chen M*. An ultrasensitive ESIPT fluorescent probe enables selective labeling and imaging of nitroreductase both in vitro and in vivo. Journal of Molecular Structure, 2026, 1349,143651.

3.Chen M, Wang K, Zhang H, Tang B, Qu Y, Luan J, Luo M, Li H, Luo C, Luo Z*, Sun X*, Shen L*. A highly sensitive ESIPT fluorescent probe for visualization of HK2-mediated lung cancer progression via imaging nitroreductase. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2026, 345, 126845.

4.Xiang T, Lin S, Tang B, Zhang H, Luan J, Qu Y, Wang K, Wu W, Shen Z, Ma W, Zhao H, Li H, Luo M, Luo Z*, Shen L*, Dong X*, Chen M*. A novel ultra-sensitive fluorescent probe for monitoring and imaging drug-induced/inhibited ferroptosis-mediated liver injury model via peroxynitrite fluctuations. Microchemical Journal,2025, 209, 112833.

5.Ma W, Tang B, Zhang H, Qu Y, Luan J, Wang K, Chen W, Wang X, Liu X, Zhao H, Li H, Luo M, Luo Z*, Shen L*,Chen M*. Small-molecule fluorescent probes for imaging intracellular amyloid toxicity induces ferroptosis via HClO fluctuation in Alzheimer’s disease. Analytica Chimica Acta,2025, 1371, 344485.