冷帆

单位

湖北医药学院基础医学院

所属学科

基础医学-药理学与毒理学

生物学-生物化学与分子生物学

职称、职务

副教授-硕士研究生导师

E-mail

fanleng@whu.edu.cn

研究方向

1.医用高分子材料

2.肿瘤综合治疗

个人简介

冷帆，博士，副教授，硕士研究生导师，入选2025年湖北省青年科技人才晨光托举工程。主要从事医用高分子材料和肿瘤综合治疗的研究。主持国家自然科学基金青年科学基金项目(C类)、湖北省科技厅联合基金项目、湖北省教育厅中青年项目、湖北省卫健委青年项目各1项。近5年以第一/通讯作者在Journal of Nanobiotechnology、CarbohydratePolymers、International Journal of Biological Macromolecules等JCR 1区期刊发表论文6篇。

代表作

1. Fan Leng, Sai Lei, Bin Luo, Siyao Lv, Long Huang, Xulin Jiang. Size-tunable and biodegradable thrombin-functionalized carboxymethyl chitin microspheres for endovascular embolization.Carbohydrate Polymers, 2022, 286, 119274.

2. Fan Leng, Taotao Li, Tongfei Li, Cong Xie, Xulin Jiang. Electron beam irradiation modified carboxymethyl chitin microsphere-based hemostatic material with strong blood cell adsorption for hemorrhage control.Biomaterials Science, 2023, 11, 5908.

3. Xiang-Yi Zhao¹, Jing-Yu Lu¹, Liang Zheng¹,…Xulin Jiang*, Yan Tan*, Tong-Fei Li*,Fan Leng*. Curcumin-loaded platelets with hydroxypropyl chitin hydrogel composite system through photo-activation for effective hemostasis management and wound healing.International Journal of Biological Macromolecules, 2025, 314, 144291.

4. Fan Leng¹, Sai Lei¹, Si-Han Zhang¹, …Enfu Du*, Ning Han*, Tong-Fei Li*.Functional doxorubicin and iron ions dual-loaded carboxymethyl chitin-based microspheres for hepatocellular carcinoma therapy via embolization, ferroptosis, and autophagy-mediated HIF-1α inhibition,International Journal of Pharmaceutics, 2026, 692, 126628.

5. Qiaoli Yi¹, Fada Xia¹, …Zhijie Xu*,Fan Leng*, Xiaokang Wang*, Yuanliang Yan*.Nano-hydrogel-based delivery system for dihydroartemisinin to enhance cuproptosis and synergize with anti-PD-1 therapy in triplenegative breast cancer,Journal of Nanobiotechnology, 2026, 24, 893.